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Bone Marrow or stem cell transplant is a surgical procedure. In this surgery process healthy stem cell is transplanted in your body. Before starting of the surgery at first you have to take chemotherapy to kill all the diseased cells and unable to work bone marrow in your body .



  • Procedure Type:  Surgical Procedures
  • Function: To remove a diseased Cell stem from your body and implant a healthy cell stem in your body
  • Pain Intensity level: Less Invasive

Bone Marrow Transplant Cost in India

Starting from INR 14,00,000

  • Procedures Duration: 1-2 Hours
  • Hospitals Stay: 3 – 4 weeks
  • Types of Anesthesia: General

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Preceding your transplant surgery, you will have to undergo several tests to determine what category of bone marrow cells you require. You might have to undergo radiation or chemotherapy to slaughter off all cancer cells before you grow the new stem cells.

Bone marrow transplants take up to a week. Therefore, making arrangements before your first transplant session is necessary. These include the following:

  • Stay near the hospital for your family
  • insurance coverage, payment of bills, and other financial concerns
  • taking medical leave from work
  • clothes and other necessities
  • arranging travel to and from the hospital

Throughout the course of medication, your immune structure will be bargained, affecting its capability to fight infections. Consequently, you will stay in a distinct segment of the hospital that is held in reserve for people receiving bone marrow transplants. This decreases your risk of being exposed to anything that could cause an infection. Don’t hesitate to fetch a list of questions to inquire from your doctor. The transplant procedure is a complex procedure and has some serious reverse side effects, if you anyhow feel led back or emotionally exhausted you may take help from a counselor.

On average, the pain from the surgery is reported to be short-lived, average, and less than predicted. Some studies show that the pain is connected to the duration and difficulty of surgery. Pain is pointedly reduced when an experienced doctor takes less than 10 minutes to complete the operation. Another important factor is your anxiety level. People who were knowledgeable about their procedure report experiencing a lot of painlessness often. People also report lower levels of pain with subsequent biopsies.

When the new stem cells enter your body, they travel through your blood to your bone marrow. In time, they multiply and begin to make new, healthy blood cells. This is called engraftment. It usually takes several weeks before the number of blood cells in your body starts to return to normal. In some people, it may take longer. In the days and weeks after your bone marrow transplant, you’ll have blood tests and other tests to monitor your condition. You may need medicine to manage complications, such as nausea and diarrhoea. After your bone marrow transplant, you’ll remain under close medical care. If you’re experiencing infections or other complications, you may need to stay in the hospital for several days or sometimes longer. Depending on the type of transplant and the risk of complications, you’ll need to remain near the hospital for several weeks to months to allow close monitoring. You may also need periodic transfusions of red blood cells and platelets until your bone marrow begins producing enough of those cells on its own. You may be at greater risk of infections or other complications for months to years after your transplant. You’ll have periodic lifelong follow-up appointments with your doctor to monitor for late complications.

If your bone marrow transplant is using stem cells from a donor, your doctors may prescribe medications to help prevent graft-versus-host disease and reduce your immune system’s reaction.

After your transplant, it takes time for your immune system to recover. During this time, you may be given medications to prevent infections.

Some of your dietitian’s recommendations may include:

  • Following food safety guidelines to prevent foodborne infections
  • Eating a wide variety of healthy foods, including vegetables; fruits; whole grains; lean meats, poultry and fish; legumes; and healthy fats, such as olive oil
  • Limiting salt intake
  • Restricting alcohol
  • Avoiding grapefruit and grapefruit juice due to their effect on a group of immunosuppressive medications.

After your bone marrow transplant, regular physical activity helps you control your weight, strengthen your bones, increase your endurance, strengthen your muscles and keep your heart healthy. As you recover, you can slowly increase your physical activity. Taking steps to prevent cancer is even more important after your transplant. Don’t smoke. Wear sunscreen when you’re outside, and be sure to get the cancer screenings your doctor recommends.

A bone marrow transplant poses numerous risks. Some people experience minimal problems with a bone marrow transplant, while others can have serious complications that require treatment or hospitalization. Sometimes, complications are life-threatening. Your particular risks depend on many factors, including the disease or condition that caused you to need a transplant, the type of transplant, and your age and overall health.

Other factors that influence the outcome are the transplant type and how good of match the donor marrow is. Another important factor is how bone marrow transplant is done. Whether you went through radiation procedure or chemotherapy procedure before your bone marrow transplant and the dosage of these procedures matters to the outcome of your transplant. The risk of complications can vary from person to person. In rare cases those undergoing a transplant may have to be hospitalized and treated for complications that arise, some may even be life threatening.


Possible complications from a bone marrow transplant include:

  • Graft-versus-host disease (in this, the donor cells transplanted through the bone marrow transplant procedure start to harm your body)
  • Stem cell (graft) failure
  • Organ damage
  • Infections
  • Cataracts
  • Infertility
  • New cancers
  • Death
    • Impaired taste
    • A prolonged headache.
    • Drop-in your blood pressure
    • Chances of contracting high ever.
    • Chest pain.
    • Nausea
    • Hives
    • Breathing difficulties

Your doctor can explain your risk of complications from a bone marrow transplant. Together you can weigh the risks and benefits to decide whether a bone marrow transplant is right for you.

One of the most important factors to be careful about after a bone marrow transplant is the risk of infection. You’re more vulnerable to bacteria, viruses, and funguses during the first 6 weeks after the transplant. Your doctor may suggest antibiotics to reduce any risks of infection. You can also take steps such as washing hands with antibacterial soap or alcohol-based sanitizer, staying away from people who are sick, and wearing a mask and gloves in public. You should visit your doctor immediately in case you have the following symptoms:

  • Higher temperature than 100.4-degree F
  • Flushed face and sweating
  • Unusual pain or swelling in the body
  • Blurred vision

You might be given radiation or chemotherapy or both by the bone marrow specialist. This is done before the bone marrow transplant procedure. There are two ways in which this is done.

  • Mini transplant or reduced-intensity treatment is a process in which radiation and chemotherapy are given to you in smaller doses. This is generally for the elderly and those people who are already suffering from health complications.
  • Ablative treatment is a process in which either radiation, chemotherapy, or a combination of both of the treatments is given to you in high doses. This is used to kill cancer cells that are in the body. Note that even the healthy cells in the bone marrow that are present are killed in this process.

The reason conditioning process is done is to suppress your immune system, destroy cancer cells (if you are suffering from a type of cancer) and allow your bone marrow to be ready for the new healthy stem cells that are going to be transplanted. The conditioning process can have one or more side effects such as organ complications, fatigue, hair loss, vomiting, cataracts, infertility, mouth ulcers, and diarrhoea.

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 (Hematopoietic Stem Cell Transplantation)

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    Our Associated Best Hematopoietic stem cell transplantation (Bone Marrow Transplant) Treatment Hospitals in India for International Patients

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    Top Surgeons for Hematopoietic stem cell transplantation (Bone Marrow Transplant)

    Well , undergoing a transplant surgery you should always rely and opt for a highly qualified surgeon. Above all, when it concerns the welfare of the patients the following top 10 verified bone marrow transplant surgeons ensure a speedy and comfortable recovery along with the best medically prescribed recommendations.

    Dr. Mansi Sachdev

    MBBS, MD (Pediatrics),Fellowship (Pediatric Bone Marrow Transplant)
    Consultant, Senior Surgeon- Bone Marrow Transplant (BMT)
    Fortis Hospital  | Fortis Hospital , Gurugram

    Doctor Available Now At Fortis Hospital India

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    Dr. Radheshyam Naik-Aster CMI Hospital

    Dr. Radheshyam Naik

    MBBS, MD, DM,  Hematology Surgery | Bone Marrow Surgeon (BMT)
    Aster CMI Hospital | Aster CMI hospital, Bangalore

    Book Appointment

    Dr. Chezhian Subash MBBS, MRCP (UK), FRCP-Pathology Hematology Specialist- MIOT International Hospital

    Dr. V Baskaran

    Director, HOD Of Gastro and Laparoscopic Surgeon, Transesophageal Echocardiography- TEE, BMT
    MIOT International Hospital | MIOT International Chennai

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    Dr. Asish Shah- Aster RV Hospital

    Dr. Ashish Shah

    Lead Consultant- Laparoscopic Surgeon, GI, Bariatric & Robotic Surgery
    Aster RV Hospital| Aster RV Hospital, Bangalore 

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    Dr. Raja M A

    MBBS, MD, MRCP(UK), Oncology board certified
    Head Consultant, Doctor, Bone Marrow Transplant (BMT)
    Apollo Chennai Hospital | Apollo Hospital, Chennai

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    Dr. Sameer A. Tulpule- Kokilaben Ambani Hospitaal

    Dr. Sameer A. Tulpule

    MBBS, MD (Gen Med), MRCP (UK), FRCPath 
    Kokilaben Dhirubhai Ambani Hospital and Medical Research institute| Kokilaben Hospital, Mumbai

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    Dr. Joydeep Chakraborty- Peerless Hospital

    Dr. Joydeep Chakraborty

    MBBS, MD, Surgeon
    Bone Marrow Transplant (BMT)
    Columbia Asia Hospital | Columbia Asia Hospital, Sarajpur Road, Bangalore

    Book Appointment

    Dr. T Narender Kumar

    MBBS, Hons. Senior. Consultant
    General & Minimally Surgery, Bone Marrow Surgeon (BMT)
    KIMS Hospital | KIMS Hospital, Hyderabad

    Book Appointment

    Kamlesh Khandelwal-Wockhardt Hospital

    Dr. Kamlesh Khandelwal

    MBBS, MS, Consultant, Director
    General Surgery, Fellowship – Minimally Invasive Surgery, Laparoscopic Surgery
    Wockhardt Hospital | Wockhardt Hospital, Mumbai

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    Dr. Rahul Naithani-Max Healthcare

    Dr. Rahul Naithani

    Bone Marrow Transplant (BMT) Surgeon
    MAX Super Specialty Hospital | MAX Super Specialty Hospital, Shalimar Bagh 

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    Top 10 Best Top Surgeons for Bone Marrow Transplant (BMT) Surgery 

    Dr. Anju Jain

    MBBS, MS(General Surgery), MD.
    Consultant- Surgeon, Bone Marrow Transplant
    Fortis Hospital Kolkata

    Doctor Available Now At Fortis Hospital India

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    Dr. Nuthan Kumar M K

    Associate Consultant, Bone Marrow Transplant
    Fortis Hospital

    Doctor Available Now At Fortis Hospital India

    Book Appointment

    Dr. Sohini Chakraborty

    MBBS, MD, FMAS, FNB Pediatric Haemato Oncology | Bone Marrow Transplant Suegery
    Fortis Hospital

    Doctor Available Now At Fortis Hospital India

    Book Appointment

    Dr. Vikas Dua

    MBBS, MD (Paediatrics ) , FNB (Paediatric Haematology Oncology, Bone Marrow transplant, Fortis Hospital

    Doctor Available Now At Fortis Hospital India

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    Dr. Niti Raizada Narang-Fortis Hospital

    Dr. Niti Raizada Narang

    MBBS, MD – General Medicine, DNB – General Medicine, DM – Medical Oncology, ESMO, MRCP (UK) | Bone Marrow Transplant | Fortis Hospital

    Doctor Available Now At Fortis Hospital India

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    What is a Bone Marrow Transplant?

    A medical procedure to replace damaged, diseased, infected or destroyed bone marrow is known as bone marrow transplant. Bone Marrow is a spongy substance or tissue found in the centre of the bones which is responsible for creating:

    Red Blood Cells (RBC) which is responsible for carrying nutrients and blood                      throughout the body.

    White Blood Cells (WBC) which wrestles infection.

    Platelets responsible for the generation of clots.

    HSCs or Hematopoietic Stem Cells are immature or young blood forming stem cells that the bone-marrow contains which later travels out the marrow into the blood when they mature. Bone marrow is a pivotal part of your anatomyas it is responsible for the proper functioning of your immune responses. If your bone marrow is ailing or unsound and there aren’t enough white blood cells, red blood cells, or platelets, then your body’s immune responses grow weak and you become prone to infections, disorders, and diseases further resulting to lethal infections. Bone Marrow transplant takes place when the bone marrow in your body breaks down and is unable to carry out its functions. The reason of bone marrow damage differs from person to person and sometimes it is difficult to ascertain bone marrow disease symptoms.

    A bone marrow transplant could be recommended by your bone transplant surgeon if your bone marrow indicates an incompetence to fabricate stem cells. Bone marrow transplant helps people suffering from cancer-related diseases and in the case of bone marrow damage due to extended chemotherapy and radiation exposure. With the help of a bone marrow transplant, your bone marrow can be redeemed as new stem cells will accelerate the process of stem cell production.


    There are two major types of bone marrow transplants. The type used will depend on the reason you need a transplant.

    1. Autologous Transplant Surgery

    Autologous transplants are a surgical process where a person’s own stem cells are used. They involve reaping your cells before emerging the method of healing your cells through chemotherapy or radiation. After the treatment is done, your own cells are returned to your body. But this process is only available if you have a healthy bone marrow. However, it reduces the risk of some serious complications, including GVHD.

    1. Allogeneic Transplants

    Allogeneic transplant is a surgical process in which you need a donor and the donor’s stem cells are used provided the donor has a close genetic match. Usually, an appropriate relative is the best choice, but genetic matches can also be found from a benefactor registry. If your cells are completely damaged then you need an allogeneic transplant though it increases the risk of GVHD. You’ll also probably be asked to stay on medications so that your new stem cells are not attackedThis can leave you susceptible to illness.

    The success of an allogeneic transplant depends on how closely the donor cells match your own.


    1. I am hesitant whether I am suitable for a bone marrow transplant. What should I do?

    You need to realize that having fears about bone marrow transplant is normal. You should jot down all the questions you have and speak to your doctor about them. The key is for you to be comfortable with the procedure before it begins. Don’t hesitate to ask your doctor all the questions you have. If you think that stress is negatively impacting you and becoming unmanageable, then it is a good idea to speak to a counsellor. Speaking to your family about the procedure and preparing them is a good idea so they are aware of what to expect. Support groups are available to help you navigate through the stress and apprehensions of the procedure. These support groups can also help you conduct adequate research online about the best hospital for bone marrow transplant in India where you can receive the best medical care. This will go a long way in alleviating your concern.

    1. How long will it take for me to restart my normal actions after the transplant procedure?

    After the bone marrow transplant, you will be closely monitored by the doctors as they                       will be on the lookout for an increase in blood cell count and any discomfort you might experience. The complete recovery might take a year but it depends on lots of factors. These include your age, health, radiation, chemotherapy, the condition for which you are being treated, and the donor match if you had an allogeneic transplant. If the transplant is deemed successful (Stem cells are being produced), then you can resume your normal daily activities.

    1. What is the bone marrow transplantation cost in India?

    The bone marrow transplant cost depends on many factors such as the type of transplant and the location of where you are getting the transplant. This is why after the appropriate tests are done, your doctor can give you an estimate of the bone marrow transplantation cost. Rest assured that the cost of bone marrow transplant in India is lesser than if you get it done from other countries. The bone marrow transplant cost in India can vary from hospital to hospital, hence it’s necessary that you do your research online and take a quote from multiple hospitals before choosing to proceed. However, make sure that the quality of healthcare you receive is not compromised when looking for affordability.

    1. Which is a safer alternative transplant procedure;

    allogeneic or autologous bone marrow transplant?

    Getting any type of bone marrow transplant is risky. However, usually using autologous bone marrow transplant is more advantageous because you are using your own body’s stem cells inside of ones from a donor. The big risk with allogeneic bone marrow transplant is the incompatibility issue. Finding a perfect match can be tough and there is a higher risk of having complications such as GVHD among others. There might be a requirement for you to take medications so that your body cells don’t end up attacking the donor stem cells. This can make you more prone to health problems.

    1. Can I exercise after a bone marrow transplant?

    Once your bone marrow transplant has been a success, you can start to exercise. However, it is a good idea to start slow and then as you get better you can increase the intensity of the exercise accordingly. Your doctor will help you create an exercise plan that is tailored to your needs and requirements.

    1. How long should I stay at the hospital after the transplant procedure has completed?

    This depends entirely on what you are being treated for and the location of the bone marrow transplant. Sometimes, people don’t need to stay in the hospital overnight after the procedure but others do. It depends on the individual situation. Sometimes due to high doses of radiation therapy and chemotherapy you might need to stay in the hospital for a much longer time. Your doctor will inform you about the length of your stay so that you can make arrangements accordingly.

    1. How do I know which type of bone marrow transplant procedure is appropriate for me?

    It’s best to discuss with your transplant physician as to which treatment option will best suit your specific diagnosis. In case you have any doubts about which transplant type your physician has recommended, you can contact your transplant coordinator. The coordinator can help in determining the type of transplant you’ll receive and can even schedule an appointment with your designated physician to review your treatment option.

    1. Will my blood count matter during the bone marrow transplant procedure?

    While the transplant is happening, there can be a dip in your blood cells (WBCs, RBCs, PLTs). This is why blood counts are monitored closely during the transplant. Before the transplant, your complete blood count or CBC is monitored for some weeks. The CBC gives information on the count of white blood cells (WBCs), red blood cells (RBCs), and platelets in your blood. The ideal WBC count should be between 4,000 and 10,000. If your WBCs fall below 1,000 then it can cause complications. The measurement values for RBCs are hemoglobin (Hgb) and hematocrit (Hct). Hgb should be somewhere between 14 and 18 and Hct should be somewhere between 37 and 52. In case of platelets, the count should be between 150,000 and 400,000.

    1. What are the risks of infection from an unrelated bone marrow transplant?

    It’s best to match the stem cells of the donor before a transplant is done. You are at a lower risk of getting infections from an unrelated bone marrow transplant if:

    • Your age is less. Studies show that young people react better to transplant as compared to older people
    • You receive stem cells from someone in your family, can be a brother or sister
    • You don’t suffer from any other health concerns.
    1. Is it possible to lead a normal life after a bone marrow transplant?

    One of the things you have to keep in mind is that after a transplant, it takes a lot of time to recover. The transplant can take some weeks or months to be completed. After that, you’re free to go home. It’s best to have a medical plan in mind so that you can take care of yourself better. You can also check with friends and family for help. During the first few months, you’ll feel weak and more tired than usual. There can be a sharp change in your hunger and how you smell and taste food. Since all of your cells are growing, it may take some time for you to get back to your normal activities.

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